منابع مشابه
Angiogenesis and inflammation in carotid atherosclerosis.
Carotid atherosclerosis is a leading cause of cerebrovascular events. The control of cardiovascular risk factors, i.e. tobacco smoking, alcohol abuse, hypertension, dyslipidemia, diabetes and obesity proved to reduce number of fatal and non-fatal strokes but failed to prevent important number of them. Screening for biomarkers in individuals at high risk of symptomatic vascular disease helped to...
متن کاملAngiogenesis and atherosclerosis. The mandate broadens.
Among the most exciting developments in vascular medicine is the targeting of specific molecular regulators of blood vessel growth and development for therapeutic benefit. Angiogenesis, whether physiological, such as occurs during embryogenesis, or pathological, such as occurs during wound healing and tumor progression, requires a highly coordinated series of events that includes endothelial ce...
متن کاملPlaque angiogenesis versus compensatory arteriogenesis in atherosclerosis.
Many atherosclerotic lesions are vascularized by a network of capillaries that arise from the adventitial vasa vasorum.1 These capillaries may be important regulators of plaque instability. Reflecting their inflammatory microenvironment, the capillaries are immature endothelial tubes with disorganized branching, fragile and prone to rupture. The accumulation of erythrocytes after intraplaque he...
متن کاملThe role of monocytes in angiogenesis and atherosclerosis.
New vessel formation inside the arterial wall and atherosclerotic plaques plays a critical role in pathogenesis of heart attacks and strokes. The 2 known mechanisms resulting in the formation of new vessels within the plaque are local ischemia and inflammation. Blood monocytes play an important role in both processes. First, they express receptors for vascular endothelial growth factor and some...
متن کاملCancer and atherosclerosis: the broad mandate of angiogenesis.
The vasa vasorum consist of blood vessels that vary in size from vessels with single or multiple smooth muscle cell layers to simple endothelial channels. In all but large and/or atherosclerotic vessels, the vasa vasorum are confined essentially to the adventitia of the blood vessel wall.1 This microcirculatory system presumably exists for the purpose of nourishing large and medium blood vessel...
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ژورنال
عنوان ژورنال: Ensho
سال: 1996
ISSN: 0389-4290,1884-4006
DOI: 10.2492/jsir1981.16.77